Respect the altitude
You're at 2,240m — go easy day one
Mexico City is high, and it sneaks up on you: you'll get winded on stairs and one mezcal hits like three. Drink way more water than you think you need, take day one slow, and don't schedule the pyramids-and-a-big-night on your first 24 hours. The hangovers up here are legendary for a reason.